We all like the blueberry, Blueberry pancakes make any breakfast seem special. In earlier studies, the blueberry shows an important role in protection against 17β-estradiol (E2)-mediated mammary tumorigenesis. Berries are gaining increasing importance lately for their chemopreventive and therapeutic potential against several Cancers.

Berries have received much attention lately due to their cancer chemopreventive potential. There is growing evidence from in vitro and in vivo studies that consumption of fruits and vegetables is associated with reduced risk of developing cancer. Berries are rich in anthocyanins, which are considered to be a good candidate for preventing the development of cancer by protecting cells. This study tested both preventive and therapeutic activities of diet supplemented with whole blueberry powder (50:50 blend of Tifblue and Rubel). The consumption of BB can be used as an effective strategy for the treatment of E2-associated breast cancer and possible prevention of its relapse and metastasis. Our study demonstrates the chemopreventive and therapeutic potential of blueberry and advances our understanding of the working mechanisms in search of potential future drugs.

Jeyabalan J, Aqil F, Munagala R, et al. Chemopreventive and therapeutic activity of dietary blueberry against estrogen-mediated breast cancer[J]. Journal of agricultural and food chemistry, 2013.